Abnormal GABAergic Function and Negative Affect in Schizophrenia

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Abnormal GABAergic function and face processing in schizophrenia: A pharmacologic-fMRI study.

The involvement of the gamma-aminobutyric acid (GABA) system in schizophrenia is suggested by postmortem studies and the common use of GABA receptor-potentiating agents in treatment. In a recent study, we used a benzodiazepine challenge to demonstrate abnormal GABAergic function during processing of negative visual stimuli in schizophrenia. This study extended this investigation by mapping GABA...

متن کامل

Association between abnormal REM sleep and negative symptoms in schizophrenia.

Although shortened rapid eye movement (REM) sleep latency, increased REM density, and decreased slow-wave sleep (SWS) are considered characteristic features of endogenous depression (Kupfer et al., 1978), several studies have reported similar findings in schizophrenic patients (reviewed in Zarcone et al., 1987). The latter observed that on the basis of REM abnormality, medication-free schizophr...

متن کامل

Anhedonia, positive and negative affect, and social functioning in schizophrenia.

This study examines the relationship between anhedonia and the trait dimensions of positive affect (PA) and negative affect (NA) in schizophrenia. The relationship between poor social functioning in schizophrenia and these individual differences in affectivity is also examined. Schizophrenia outpatients (n = 37) and normal controls (n = 15) were assessed at a baseline evaluation and again appro...

متن کامل

Cognitive regulation of negative affect in schizophrenia and bipolar disorder.

Schizophrenia (SZ) and bipolar disorder (BD) exhibit common cognitive deficits that may impede the capacity for self-regulating affect. We examined the use of particular cognitive strategies for regulating negative affect in SZ and BD, and their associations with levels of mood symptomatology. Participants were 126 SZ, 97 BD, and 81 healthy controls (HC) who completed the Cognitive Emotion Regu...

متن کامل

The relationship between positive and negative affect and psychosocial function in the corona epidemic: the mediating role of psychological resilience

The aim of this study was to investigate the mediating role of psychological resilience in the relationship between positive and negative emotions and the psychosocial functioning of individuals during the corona. The design of the present study was descriptive correlation and path analysis was applied. The statistical population included Iranian adults, of which 461 people participated in this...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Neuropsychopharmacology

سال: 2013

ISSN: 0893-133X,1740-634X

DOI: 10.1038/npp.2013.300